Peran Bedah Rekonstruksi Uretra dalam Memulihkan Fungsi Reproduksi pada Pria dengan Cedera Urogenital

Authors

  • Muhammad Fachrurrozy Basalamah Rumah Sakit Haji Jakarta, Jakarta
  • Kemal Akbar Suryoadji Fakultas Kedokteran, Universitas Indonesia, Jakarta
  • Abdul Hafiidh Surya Putra Fakultas Kedokteran, Universitas Indonesia, Jakarta

DOI:

https://doi.org/10.53088/griyawidya.v3i2.1688

Keywords:

Male infertility, Urethral injury, Urethral reconstruction, Anastomotic urethroplasty, Buccal mucosa graft

Abstract

Background:  This review evaluates urethral reconstruction’s effectiveness in fertility restoration.

Methods: A systematic review was conducted using PubMed, Scopus, and Cochrane databases. Studies on anastomotic urethroplasty, buccal mucosa graft (BMG) urethroplasty, and acellular dermal matrix (ADM) grafts were analyzed. Outcomes included patency rates, ejaculatory function, erectile function, and fertility restoration, along with postoperative complications and long-term reproductive outcomes.

Results: Anastomotic urethroplasty achieved >90% patency for strictures <2 cm, with 100% antegrade ejaculation restoration in pelvic fracture cases. BMG urethroplasty showed an 85.7–100% success rate for strictures >3 cm, with 76% reporting improved ejaculation force. ADM grafts had a 94% success rate in complex cases. Erectile dysfunction occurred in 9.7% but resolved within 6–20 months.

Discussion: Urethral reconstruction restores patency and ejaculation in >85% of cases, but fertility outcomes depend on factors like testicular atrophy and neurovascular integrity. Non-transecting techniques reduce vascular complications, and early intervention aids spermatogenesis preservation. A multidisciplinary approach integrating andrology and assisted reproductive techniques is crucial.

References

Al-Gammal, M. I., Abdullah, A. M., Abul-Fotouh, A. F., & Selmy, G. I. (2020). Augmented anastomotic urethroplasty for long segment bulbous urethral strictures. Al-Azhar Medical Journal, 49(2), 825–838. https://doi.org/10.21608/amj.2020.82597

Aodi, J., Ying, L., Chengyang, S., & Hongfeng, Z. (2024). Acellular dermal matrix in urethral reconstruction. Frontiers in Pediatrics, 12, https://doi.org/10.3389/fped.2024.1342906

Barratt, C. L. R., De Jonge, C. J., Anderson, R. A., et al. (2021). A global approach to addressing the policy, research and social challenges of male reproductive health. Human Reproduction Open, 2021(1) https://pubmed.ncbi.nlm.nih.gov/33768166/

Calleja Hermosa, P., Campos-Juanatey, F., Varea Malo, R., Correas Gómez, M. Á., & Gutiérrez Baños, J. L. (2021). Sexual function after anterior urethroplasty: A systematic review. Translational Andrology and Urology, 10(6), 2554–2573. https://doi.org/10.21037/tau-20-1307

Cooperberg, M. R., McAninch, J. W., Alsikafi, N. F., & Elliott, S. P. (2007). Urethral reconstruction for traumatic posterior urethral disruption: Outcomes of a 25-year experience. The Journal of Urology, 178(5), 2006–2010. https://doi.org/10.1016/j.juro.2007.07.020

Esteves, S. C., Miyaoka, R., & Agarwal, A. (2011). Surgical treatment of male infertility in the era of intracytoplasmic sperm injection – new insights. Clinics (Sao Paulo), 66(8), 1463–1478. https://pubmed.ncbi.nlm.nih.gov/21915501/

Huang, B., Wang, Z., Kong, Y., Jin, M., & Ma, L. (2023). Global, regional and national burden of male infertility in 204 countries and territories between 1990 and 2019: An analysis of global burden of disease study. BMC Public Health, 23(1), 2195. https://doi.org/10.1186/s12889-023-16793-3

Mora, R., Nabhani, J., Bakare, T., Khouri, R., & Samplaski, M. (2023). The effect of testicular trauma on male infertility. Human Fertility (Cambridge), 26(5), 1093–1098. https://doi.org/10.1080/14647273.2022.2135464

Tabei, S. S., Lippold, B., Baas, W., & Murphy, G. (2024). Penetrating posterior urethral injuries: Case report and management strategies. Case Reports in Urology, 2024, https://doi.org/10.1155/2024/7839379

Yeboah, E. D., & Marmar, J. L. (1994). Urethral stricture and semen quality. International Journal of Fertility and Menopausal Studies, 39(6), 310–315.

Zheng, L., Wang, L., Jiang, H., & Jiang, T. (2024). Retrograde ejaculation due to posterior urethral stricture: A rare case report. American Journal of Men's Health, 18(5), 15579883241276986.

Downloads

Published

2024-06-29

How to Cite

Basalamah, M. F., Suryoadji, K. A., & Surya Putra, A. H. (2024). Peran Bedah Rekonstruksi Uretra dalam Memulihkan Fungsi Reproduksi pada Pria dengan Cedera Urogenital. Griya Widya: Journal of Sexual and Reproductive Health, 3(2), 78–86. https://doi.org/10.53088/griyawidya.v3i2.1688